Cho JH, Kim HJ. The effect of continuous positive airway pressure on cardiopulmonary coupling. Sleep Breath 2017; 21(2): 341-345. DOI: 10.1007/s11325-016-1419-8
To investigate cardiopulmonary coupling (CPC) as a tool for evaluating the efficacy of continuous positive airway pressure (CPAP) in the treatment of obstructive sleep apnea (OSA).
The apnea-hypopnea index, CPC variables, and sleep stage (%) during the first 2 h of the sleep study did not differ between the PSG-only and CPAP titration groups. A comparison of data collected over the first 2 h and that collected over the rest of the sleep study revealed that high-frequency coupling (HFC) increased, and low-frequency coupling (LFC) and elevated LFC (e-LFC) decreased only for the CPAP titration group, while they did not change for the PSG-only group.
CPC effectively reflects the treatment effect of CPAP when compared with an electroencephalography-based sleep stage assessment.