Kim W, Na J. Sleep Quality Change After Catheter Ablation in Paroxysmal Atrial Fibrillation and Relation of Sleep Stability to the Recurrence – 24 Hour Holter Based Cardiopulmonary Coupling Analysis. American Heart Assn. Circulation. 2017; 136: A19496
Sleep instability is highly prevalent in patients with cardiovascular disease (CVD) and evidence supports a causal association of sleep instability with CVD. We investigate the impact of radio-frequency catheter ablation (RFCA) on sleep instability in patients with paroxysmal atrial fibrillation (pAF) and the effect of sleep stability on recurrence of AF utilizing cardiopulmonary coupling (CPC) analysis.
Sleep quality was improved after RFCA in patients with pAF. Furthermore, the recurrence rate was significantly lower after RFCA in patient who had pre-RFCA sleep instability (Low Frequency Coupling, LFC; Unstable sleep ≥50.3%).
These results suggest that RFCA can influence sleep quality and sleep quality assessment by CPC-analysis of routine 24-hr Holter study can be a predictable marker of recurrence after RFCA in patients with pAF.