Reference:
Kim W, Na J. Sleep Quality Change After Catheter Ablation in Paroxysmal Atrial Fibrillation and Relation of Sleep Stability to the Recurrence – 24 Hour Holter Based Cardiopulmonary Coupling Analysis. American Heart Assn. Circulation. 2017; 136: A19496
Objectives:
Sleep instability is highly prevalent in patients with cardiovascular disease (CVD) and evidence supports a causal association of sleep instability with CVD. We investigate the impact of radio-frequency catheter ablation (RFCA) on sleep instability in patients with paroxysmal atrial fibrillation (pAF) and the effect of sleep stability on recurrence of AF utilizing cardiopulmonary coupling (CPC) analysis.
Conclusions:
Sleep quality was improved after RFCA in patients with pAF. Furthermore, the recurrence rate was significantly lower after RFCA in patient who had pre-RFCA sleep instability (Low Frequency Coupling, LFC; Unstable sleep ≥50.3%).
Practical Significance:
These results suggest that RFCA can influence sleep quality and sleep quality assessment by CPC-analysis of routine 24-hr Holter study can be a predictable marker of recurrence after RFCA in patients with pAF.