Hilmisson H, Lange N, Duntley S. Sleep apnea detection: accuracy of using automated ECG analysis compared to manually scored polysomnography (apnea hypopnea index). Sleep Breath 2018; 23(1): 125-133. DOI: 10.1007/s11325-018-1672-0
Measuring sleep quality and sleep apnea (SA) at the point of care utilizing data that is already collected is feasible and cost effective, using validated methods to unlock sleep information embedded in the data. The objective of this study is to determine the utility of automated analysis of a stored, robust signal widely collected in hospital and outpatient settings, a single lead electrocardiogram (ECG), using clinically validated algorithms, cardiopulmonary coupling (CPC; SleepImage), to objectively and accurately identify SA.
The SleepImage method is accurate in identifying patients with moderate to severe SA with sensitivity of 100%, specificity of 81%, and agreement of 93%, LR+ (positive likelihood ratio) 5.20, LR− (negative likelihood ratio) 0.00 and kappa 0.85 compared with manual scoring of AHI.
Automated CPC analysis of stored single lead ECG data often collected during sleep in the clinical setting can accurately identify sleep apnea, providing medically actionable information that can aid clinical decisions.