Impact of Sleep-Disordered Breathing on Functional Outcomes in Ischemic Stroke: A Cardiopulmonary Coupling Analysis

Reference:
Kang DO, Kim CK, Park Y, et al. Impact of Sleep-Disordered Breathing on Functional Outcomes in Ischemic Stroke: A Cardiopulmonary Coupling Analysis [published online ahead of print, 2020 Jun 9]. Stroke. 2020;STROKEAHA119028730. doi:10.1161/STROKEAHA.119.028730

Objectives:
Cardiopulmonary coupling (CPC) analysis is an easily assessable method to evaluate sleep-disordered breathing (SDB); however, its prognostic impact in patients with acute ischemic stroke needs to be investigated. CPC analysis was performed on electrocardiogram (ECG) data collected with Holter monitoring at the early stage of noncardioembolic ischemic stroke to investigate the prognostic effect of SDB on functional impairment at the 3-month follow-up.

Conclusions:
SDB assessed by CPC analysis at the early stage of ischemic stroke could predict severe and prolonged functional impairment at 3 months.

Practical Significance:

Analyzing ECG-signals from Holter monitoring or wearable ECG-devices with CPC to calculate periodicity (eLFCnb) can help predict functional impairment in acute ischemic stroke patients.

View Publication

Impact of Sleep-Disordered Breathing on Functional Outcomes in Ischemic Stroke: A Cardiopulmonary Coupling Analysis