Electrophysiological Difference in Obstructive Sleep Apnea with and without REM sleep Behavior Disorder: Cardiopulmonary Coupling Analysis

Reference:
Song P, Park YK, Choi SJ, Joo EY. Electrophysiological difference in obstructive sleep apnea with or without REM sleep behavior disorder: cardiopulmonary coupling analysis. Sleep Medicine 2017; 40(1): 311-214. DOI: 10.1016/j.sleep.2017.11.917

Objectives:
Although rapid eye movement behavior disorder (RBD) and obstructive sleep apnea syndrome (OSA) have different pathophysiology, RBD patients with OSA appeared to have more stable sleep compared to patients with OSA and to verify it by cardiopulmonary coupling (CPC) method.

Conclusions:
In terms of autonomic-respiratory interaction analysis with CPC, RBD with OSA showed similar CPC profile (higher Low Frequency Coupling (LFC; unstable sleep) and lower High Frequency Coupling (HFC; stable sleep) than normal) but less severe than pure OSA group. It suggests that RBD may have a protective effect on OSA.

Practical Significance:
RBD may have protective effect on OSA.

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Electrophysiological Difference in Obstructive Sleep Apnea with and without REM sleep Behavior Disorder: Cardiopulmonary Coupling Analysis