ECG-derived Cardiopulmonary Analysis of Pediatric Sleep-Disordered Breathing

Reference:
Guo D, Peng CK, Wu HL, et al. ECG-derived cardiopulmonary analysis of pediatric sleep-disorder breathing. Sleep Med 2011; 12 (4): 384-9 DOI: 10.1016/j.sleep.2010.09.011

Objectives:
An ECG-derived sleep spectrogram, based on CPC analysis previously described in adults, can provide information about the severity of sleep disordered breathing (SDB) and coupled interactions of sleep modulated autonomic drive and respiration. We hypothesized that CPC algorithm-derived metrics will correlate with nasal pressure-based apnea–hypopnea scoring in pediatric population.

Conclusions:
ECG-derived sleep spectrogram metrics are correlated with nasal flow-derived respiratory abnormality in pediatric SDB.

Practical Significance:
The high correlation between CPC metrics and nasal flow derived metrics in pediatric SDB patients demonstrates an opportunity to screen for SDB and track treatment effects. 

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ECG-derived Cardiopulmonary Analysis of Pediatric Sleep-Disordered Breathing