Cardiopulmonary coupling analysis predicts early treatment response in depressed patients: A pilot study

Reference:
Qi-Meng Sun, Lu Xing, Chao Wang, Wei Liang. Cardiopulmonary coupling analysis predicts early treatment response in depressed patients: A pilot study. Psychiatry Res 2019; 276. DOI: 10.1016/j.psychres.2019.04.002 

Objectives:
This pilot study evaluated the effect of anti-depression treatment on sleep quality and symptoms of depression in patients with major depressive disorder, and identified cardiopulmonary coupling (CPC) indices for predicting early response.

Conclusions:
Our findings suggest that objective sleep quality measured by CPC analysis is useful for predicting treatment response to antidepressant treatment in patients with major depressive disorder.

Practical Significance:
CPC is a simple method to implement to measure sleep variables to predict early treatment of antidepressants on sleep quality in major depressive disorder.

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Cardiopulmonary coupling analysis predicts early treatment response in depressed patients: A pilot study