Qi-Meng Sun, Lu Xing, Chao Wang, Wei Liang. Cardiopulmonary coupling analysis predicts early treatment response in depressed patients: A pilot study. Psychiatry Res 2019; 276. DOI: 10.1016/j.psychres.2019.04.002
This pilot study evaluated the effect of anti-depression treatment on sleep quality and symptoms of depression in patients with major depressive disorder, and identified cardiopulmonary coupling (CPC) indices for predicting early response.
Our findings suggest that objective sleep quality measured by CPC analysis is useful for predicting treatment response to antidepressant treatment in patients with major depressive disorder.
CPC is a simple method to implement to measure sleep variables to predict early treatment of antidepressants on sleep quality in major depressive disorder.