Beyond the Apnea Hypopnea Index (AHI): Importance of Sleep Quality Management of Obstructive Sleep Apnea (OSA) and Related Mortality in Patients with Cardiovascular Disease

Reference:
Hilmisson H, Magnusdottir S. Beyond the Apnea Hypopnea Index (AHI): Importance of Sleep Quality management of Obstructive Sleep Apnea (OSA) and Related Mortality in Patients with Cardiovascular Disease. Sleep Medicine 2019. DOI: 10.1016/j.sleep.2019.11.424

Objectives:
To observe if the SleepImage software generated Sleep Quality Index (SQI) offers relevant clinical information additional to the Apnea Hypopnea Index (AHI) in management of hypertension in OSA patients that may reduce Cardiovascular Disease morbidity and mortality.

Conclusions:
Continuous Positive Airway Pressure (CPAP) only improved blood pressure in patients with compromised sleep quality at baseline (SQI<55) not in patients with good sleep quality at baseline (SQI>55).  Patients that improved SQI during the 12-week study period, regardless of therapy, significantly improved in blood pressure.

Practical Significance:

Improving sleep quality as part of therapy in patients with OSA and multiple cardiovascular risk factors including high blood pressure is important.

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Beyond the Apnea Hypopnea Index (AHI): Importance of Sleep Quality Management of Obstructive Sleep Apnea (OSA) and Related Mortality in Patients with Cardiovascular Disease