Schramm PJ, Thomas RJ. Assessment of therapeutic options for mild obstructive sleep apnea using cardiopulmonary coupling measures. J Clin Sleep Med 2012;8(3): 315-20 PMID: 22701390 PMCID: PMC3365091 DOI: 10.5664/jcsm.1924
To examine the efficacy of various therapeutic modalities for mild obstructive sleep apnea using cardiopulmonary coupling variables of sleep quality.
Baseline sleep quality estimated using the ratio of high-frequency and low-frequency coupling (1.03) was below the expected normal adult values ranging from 1.67-4.0. The sleep quality ratio was significantly higher (2.08) using the MAA alone compared to baseline, sleep position restriction (1.61), oxygen therapy (0.81), and the combination of MAA with oxygen (1.66).
Sleep quality measured objectively using cardiopulmonary coupling variables differentiated the efficacy of therapeutic options for mild obstructive sleep apnea.